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Robert J Linhardt Selected Research

Enzymes

1/2022Effect of high glucose on glycosaminoglycans in cultured retinal endothelial cells and rat retina.
11/2021Anti-SARS-CoV-2 Activity of Rhamnan Sulfate from Monostroma nitidum.
11/2020Prominent members of the human gut microbiota express endo-acting O-glycanases to initiate mucin breakdown.
1/2014Heparan sulfate deficiency disrupts developmental angiogenesis and causes congenital diaphragmatic hernia.
10/2010Carrageenan-induced innate immune response is modified by enzymes that hydrolyze distinct galactosidic bonds.

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Robert J Linhardt Research Topics

Disease

40Neoplasms (Cancer)
08/2023 - 10/2002
21Infections
08/2024 - 10/2003
17Inflammation (Inflammations)
04/2023 - 01/2007
11Thrombocytopenia (Thrombopenia)
12/2023 - 09/2008
11Alzheimer Disease (Alzheimer's Disease)
01/2023 - 06/2002
10Hemorrhage
01/2021 - 03/2010
9COVID-19
01/2023 - 01/2020
8Pathologic Processes
01/2022 - 09/2004
8Lung Neoplasms (Lung Cancer)
11/2021 - 03/2010
8Hepatocellular Carcinoma (Hepatoma)
01/2021 - 08/2004
7Sepsis (Septicemia)
01/2023 - 03/2014
7Neoplasm Metastasis (Metastasis)
11/2021 - 06/2012
7Thrombosis (Thrombus)
09/2021 - 05/2006
5Neurodegenerative Diseases (Neurodegenerative Disease)
02/2021 - 01/2020
4Disease Progression
06/2023 - 02/2012
4Venous Thrombosis (Deep-Vein Thrombosis)
09/2021 - 01/2003
4Hypoxia (Hypoxemia)
01/2020 - 03/2011
3Atherosclerosis
04/2024 - 07/2008
3Wounds and Injuries (Trauma)
12/2023 - 03/2014
3Carcinoma (Carcinomatosis)
08/2023 - 06/2012
3Virus Diseases (Viral Diseases)
01/2023 - 09/2002
3Endotoxemia
01/2023 - 01/2019
3Mucopolysaccharidoses
10/2022 - 06/2015
3Myocardial Infarction
01/2022 - 01/2013
3Osteoarthritis
05/2021 - 02/2010
3Communicable Diseases (Infectious Diseases)
01/2021 - 11/2013
3Colonic Neoplasms (Colon Cancer)
04/2020 - 04/2014
3Lyme Disease (Disease, Lyme)
01/2020 - 12/2017
3Lung Injury
11/2019 - 03/2014
3Hypotension (Low Blood Pressure)
10/2019 - 03/2009
3Arthritis (Polyarthritis)
12/2017 - 01/2015
3Malaria
02/2014 - 10/2003
3Breast Neoplasms (Breast Cancer)
03/2012 - 03/2010
2Human Influenza (Influenza)
08/2023 - 01/2017
2Tauopathies
11/2022 - 06/2022
2Type 2 Diabetes Mellitus (MODY)
06/2022 - 02/2020
2Stroke (Strokes)
01/2022 - 12/2020
2Hyperglycemia
01/2022 - 01/2020

Drug/Important Bio-Agent (IBA)

43Heparin (Liquaemin)FDA LinkGeneric
04/2024 - 01/2003
35GlycosaminoglycansIBA
12/2023 - 03/2003
34Heparitin Sulfate (Heparan Sulfate)IBA
04/2024 - 09/2002
25Proteins (Proteins, Gene)FDA Link
04/2024 - 10/2003
25Polysaccharides (Glycans)IBA
04/2024 - 12/2004
17AnticoagulantsIBA
04/2023 - 01/2003
10Chondroitin Sulfates (Chondroitin Sulfate)IBA
01/2022 - 08/2009
8DisaccharidesIBA
01/2020 - 04/2007
7AntibodiesIBA
09/2021 - 11/2006
7OligosaccharidesIBA
04/2021 - 01/2007
7Proteoglycans (Proteoglycan)IBA
12/2020 - 01/2007
6Hyaluronic Acid (Hyaluronan)IBA
01/2022 - 10/2013
5Antiviral Agents (Antivirals)IBA
08/2023 - 11/2006
5VaccinesIBA
08/2023 - 06/2015
5Heparan Sulfate Proteoglycans (Heparan Sulfate Proteoglycan)IBA
11/2022 - 10/2003
5EnzymesIBA
01/2022 - 10/2010
5Glycoproteins (Glycoprotein)IBA
05/2021 - 11/2006
5Carrier Proteins (Binding Protein)IBA
01/2021 - 01/2005
5CarbohydratesIBA
07/2020 - 01/2005
5LigandsIBA
01/2017 - 01/2004
4Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA
01/2023 - 01/2004
4Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
12/2022 - 04/2015
4Platelet Factor 4IBA
01/2022 - 06/2017
4Biomarkers (Surrogate Marker)IBA
02/2020 - 03/2014
4Dermatan SulfateIBA
10/2017 - 10/2013
3Angiotensin-Converting Enzyme 2IBA
01/2023 - 11/2020
3Apolipoproteins E (ApoE)IBA
01/2023 - 06/2002
3LipidsIBA
12/2022 - 06/2017
3Fibroblast Growth Factor Receptors (Fibroblast Growth Factor Receptor)IBA
01/2022 - 01/2004
3DNA (Deoxyribonucleic Acid)IBA
01/2022 - 03/2014
3Peptides (Polypeptides)IBA
01/2021 - 01/2018
3GlycolipidsIBA
01/2021 - 04/2014
3Low-Molecular-Weight Heparin (Heparin, Low Molecular Weight)IBA
07/2019 - 03/2010
3Antineoplastic Agents (Antineoplastics)IBA
04/2019 - 07/2016
3Syndecan-1 (Syndecan 1)IBA
10/2017 - 04/2014
3Type 2 Fibroblast Growth Factor Receptor (Fibroblast Growth Factor Receptor 2)IBA
03/2011 - 01/2004
3CarrageenanIBA
10/2010 - 04/2008
3acharan sulfateIBA
08/2010 - 03/2003
2SARS-CoV-2 spike proteinIBA
08/2023 - 01/2021
2Hemagglutinins (Hemagglutinin)IBA
08/2023 - 01/2017
2N-acetylneuraminoyllactoseIBA
08/2023 - 03/2014
2AcidsIBA
08/2023 - 04/2014
2Transforming Growth Factors (Transforming Growth Factor)IBA
01/2023 - 02/2011
2HMGB1 Protein (HMG1)IBA
01/2023 - 01/2020
2SugarsIBA
12/2022 - 10/2022
2Sulfates (Sulfates, Inorganic)IBA
12/2022 - 01/2019
2rhamnanIBA
12/2022 - 06/2020
2Therapeutic UsesIBA
12/2022 - 06/2020
2PrionsIBA
10/2022 - 01/2020
2CathepsinsIBA
10/2022 - 02/2021
2AntithrombinsIBA
01/2022 - 06/2012
2Hormones (Hormone)IBA
01/2022 - 11/2018
2Messenger RNA (mRNA)IBA
01/2022 - 07/2008
2Retinaldehyde (Retinal)IBA
01/2022 - 01/2019
2Fibroblast Growth Factors (Fibroblast Growth Factor)IBA
01/2022 - 11/2021
2Amyloid (Amyloid Fibrils)IBA
10/2021 - 09/2014
2PrebioticsIBA
10/2021 - 04/2020
2fucoidanIBA
02/2021 - 10/2018

Therapy/Procedure

20Therapeutics
04/2024 - 03/2010
2Intranasal Administration
08/2024 - 07/2020
2Ligation
01/2023 - 01/2019
2Punctures
01/2023 - 01/2019